Success Stories / AWS Native Multi-Stage Data Pipeline Implementation

AWS Native Multi-Stage Data Pipeline Implementation

A US-based precision nutrition and multi-omics diagnostics provider partnered with Matoffo to eliminate critical data processing bottlenecks that were constraining research velocity and competitive positioning.
Healthcare TechnologyTerraformWorkflow Orchestration
25 min read

Executive Summary

A US-based precision nutrition and multi-omics diagnostics provider partnered with Matoffo to eliminate critical data processing bottlenecks that were constraining research velocity and competitive positioning. Facing multi-week delays between data collection and actionable insights due to manual workflows for handling mass spectrometry data, the organization needed to scale research operations and maintain innovation leadership in the rapidly evolving precision healthcare market.

Matoffo designed and deployed a fully automated, AWS-native data pipeline leveraging serverless architecture and infrastructure-as-code to deliver elastic scalability without proportional cost increases. The solution processes 500 mass spectrometry files in under 6 hours, work that previously required weeks of manual effort and extensive Data Science team involvement.

Client Background

A fast-growing health-tech platform serving legal and insurance teams needed to turn chaotic medical records into clean, case-ready chronologies and summaries at scale. Their workloads spanned multiple jurisdictions and matter types, with case files often hundreds of pages long – scanned PDFs, mixed-quality images, and handwriting – creating slow, manual review cycles and inconsistent outputs. Enterprise buyers were pushing for stronger proof of security and compliance while expecting faster turnarounds and higher throughput. Before partnering with Matoffo, processing typically took hours per case and was hard to scale predictably across clients; the team wanted a secure, AWS-native path to standardize outputs and support 100+ concurrent cases per day without adding proportional headcount.

Client's Feedback

5.0
Review verified

"Matoffo's team demonstrated exceptional technical expertise and understanding of our business needs, designing a solution that transformed our operations."

Chief Technology Officer,

Customer Challenge

As the organization’s data volume expanded and research portfolio grew, operational stress mounted on data processing systems. Manual workflows for handling mass spectrometry data created delays, quality issues, and scalability constraints that threatened the company’s competitive position in the precision healthcare market.

Key Business Challenges:

icon

Research Velocity Constraints:

Multi-week delays between data collection and insight generation fundamentally limited research throughput. Data Science teams waited days or weeks for processing to complete before beginning analysis, extending research timelines and reducing the organization's ability to respond to emerging opportunities. In a rapidly evolving field where research velocity determines competitive position, processing bottlenecks threaten innovation leadership.
icon

Unsustainable Scaling Economics:

Each new research program required proportional increases in personnel to handle manual workflows. The organization faced a forced choice between limiting research ambition or accepting unsustainable headcount growth, as processing capacity could only expand through additional manual effort.
icon

Limited Processing Capacity:

Manual workflows for handling 500 raw mass spectrometry files created operational inefficiencies. The organization lacked automated mechanisms for parallel processing, forcing sequential execution that multiplied delays and prevented leveraging modern cloud infrastructure capabilities.
icon

Lack of Quality Assurance:

The absence of automated validation and state management meant data quality issues could propagate undetected through research workflows, undermining confidence in research outputs and compliance requirements.

These business pressures threatened the organization’s ability to deliver timely insights while maintaining profitability and competitive positioning in an increasingly AI-driven precision healthcare market where data velocity differentiates industry leaders from traditional providers.

Goals and Requirements

The client established clear, measurable objectives to transform their data processing infrastructure from a limiting factor into a competitive advantage while balancing immediate operational needs with long-term strategic requirements.

Performance Targets

  • Reduce end-to-end processing time from days to under 6 hours for 500-file research cycles, enabling same-day or next-morning insight delivery.

Financial & Operational Targets

  • Reduce Data Science team involvement in infrastructure management by 60%+ through automation, reallocating dozens of weekly hours from operational tasks to high-value analysis and research.

Scalability & Reliability

  • Design architecture capable of processing 1,000+ files as research programs expand without requiring architectural changes or performance degradation.

The Solution

Matoffo delivered a cloud-native, event-driven data pipeline built entirely on AWS managed services, prioritizing automation and operational simplicity through infrastructure-as-code.

  1. 1

    Architecture Design and Serverless Foundation

    The team conducted discovery sessions with Data Science and R&D departments to understand workflows and requirements for processing liquid chromatography-mass spectrometry data. Matoffo designed a highly available architecture leveraging AWS Step Functions as the orchestration backbone to manage state transitions and error handling. AWS Fargate was selected over AWS Lambda to run ETL code and handle time-consuming processing exceeding Lambda runtime limits. The architecture was deployed using Terraform for infrastructure and Serverless Framework for Lambda functions, creating version-controlled infrastructure ensuring reproducibility.
  2. 2

    Automated Data Ingestion and Event-Driven Triggers

    Workflow automation activates immediately when researchers deposit raw mass spectrometry files into designated Amazon S3 buckets. Event-driven triggers using S3 notifications initiate Step Functions executions automatically, eliminating manual procedures. AWS Lambda functions manage parameters and trigger executions based on file metadata. State tracking in Amazon DynamoDB prevents reprocessing of completed files, ensuring efficient resource utilization.
  3. 3

    Parallel Processing and Workflow Orchestration

    AWS Step Functions coordinates parallel execution across hundreds of files simultaneously, distributing workload across multiple AWS Fargate tasks to maximize throughput. The orchestration layer manages dependencies between processing stages, handling data validation, transformation, analysis, and quality control checks. DynamoDB tracks processing state for each file, providing real-time visibility and enabling automatic recovery from failures.
  4. 4

    Data Management and Quality Assurance

    Processed data flows through a structured data lake architecture in Amazon S3 with distinct zones for raw data, intermediate outputs, and validated results. Automated validation checks verify data quality at each stage, catching errors early. The system generates comprehensive data catalogs documenting file provenance, processing history, and quality metrics essential for research reproducibility. Pipeline reports provide visibility into throughput, error rates, and performance metrics.
  5. 5

    Monitoring, Documentation, and Knowledge Transfer

    Comprehensive monitoring tracks pipeline health, processing performance, and cost utilization. Automated alerting detects failures, quality degradations, and performance anomalies before impacting research timelines. Detailed technical documentation covers architecture decisions, deployment procedures, and operational runbooks. The Matoffo team provided knowledge transfer sessions with Data Science and DevOps teams, ensuring organizational capability to operate and extend the platform independently.

Results and Impact

Before:

Data processing required extensive manual effort, extending research cycles to weeks. Data Science teams spent significant time managing infrastructure rather than conducting analysis. Sequential processing created capacity constraints, forcing tradeoffs between research ambition and operational reality.

After:

End-to-end processing cycles reduced from weeks to under 6 hours. Complete workflow automation eliminates manual intervention. Parallel processing enables concurrent execution of multiple research cycles without performance degradation.

Quantitative Outcomes

  • 80%+ acceleration in research velocity: Processing time for 500-file cycles decreased from weeks to 6 hours, enabling rapid iteration on scientific hypotheses.

  • 85%+ reduction in infrastructure management time: Data Science teams reallocated dozens of weekly hours to high-value analysis.

  • 10,000+ files per hour processing capacity: Parallel execution dramatically increased throughput and removed previous bottlenecks.

Qualitative Outcomes

  • Researcher productivity transformation: Scientists now focus entirely on discovery rather than infrastructure management.

  • Growth enablement: The elastic architecture enables larger research programs without proportional infrastructure investment.

  • Enhanced data confidence: Automated validation improved confidence in research outputs while streamlining compliance.

Key Learnings

  • Serverless architecture is optimal for research environments with variable demand patterns.

    Containerized serverless computing proved ideal for data processing workloads characterized by unpredictable timing and variable volume. The architecture scales automatically from zero to hundreds of concurrent tasks without capacity planning, delivering operational simplicity and cost efficiency through pay-per-use economics that align costs directly with actual usage.

  • Workflow orchestration transforms independent processing steps into reliable pipelines.

    Investing in orchestration via AWS Step Functions early rather than building custom coordination logic accelerated development while improving reliability and maintainability. The orchestration layer provides automatic error handling, retry logic, and complete visibility into execution flow, transforming fragile sequential scripts into robust, manageable workflows.

Next Steps

Following successful deployment, the client plans to expand capabilities through two strategic initiatives.

  1. 1

    Expand Data Type Coverage and Partnerships

    Extend the architecture to handle genomic sequencing, metabolomic analysis, and clinical trial data, leveraging existing orchestration and infrastructure.
  2. 2

    Implement Real-Time Processing and Machine Learning

    Enrich the pipeline with streaming ingestion via Amazon Kinesis for near-real-time feedback on time-sensitive research protocols. Integrate ML models for automated pattern recognition, anomaly detection, and predictive quality scoring, moving from automated processing to automated insight generation.

Conclusion

The successful deployment of this AWS-native data pipeline marked a transformational milestone in how the client approaches research operations and competitive positioning in the precision healthcare market. By eliminating manual workflows and implementing cloud-native architecture with complete automation, the client gained a competitive advantage through the ability to process data at scale while maintaining the reproducibility essential for scientific validity.

Explore Our Case Studies

AWSGenerative AIProcess Automation

GenAI-Empowered Underwriting & Claim Processing

A premier financial-protection provider was hampered by manual document handling, underwriting, and claims review - processes that slowed policy issuance, introduced errors, and inflated operating costs.
Cloud Solution DevelopmentFinTechMachine Learning

Intelligent Bill Processing

A globally recognized financial technology provider, known for its digital wallet and spending management platform, was facing operational inefficiencies due to manual invoice processing across diverse document formats.
CI/CD AutomationCloud MigrationKubernetes

Migration From GCP to AWS/ Kubernetes Implementation

A rapidly scaling e-commerce startup serving customers across Africa was experiencing infrastructure limitations that hindered its ability to support increasing demand.
DevOps AutomationFinTechTerraform

Infrastructure & DevOps Services for Fintech Product

A fast-growing fintech that helps schools manage tuition and campus payments was struggling with slow, error-prone manual deployments.
DevOps AutomationPropTechSaaS

Cloud & Devops Services for Real Estate Product

A fast-growing real estate technology company faced challenges scaling its monolithic application, managing infrastructure manually, and delivering updates reliably across multiple environments. These limitations resulted in delayed deployments, inconsistent user experience, and mounting operational overhead.
AI document intelligenceAWS Cloud ArchitectureHealth-tech

Transforming Medical Document Processing with the AI System

A leading health-tech company serving legal and insurance teams partnered with Matoffo to replace manual review of complex medical records with an AWS-native, GenAI-powered platform.
Amazon Web ServicesCybersecurityMLOps and LLM Engineering

GenAI Augmented Security Issues and Misconfiguration Monitoring and Advisory Platform

A globally recognized cloud security provider partnered with Matoffo to transform security operations by replacing manual log analysis and misconfiguration detection with an AWS-native, GenAI-powered platform.
AI and Machine Learning ConsultingAmazon Web Services

Field Management Agents Accelerator

The Matoffo team developed an AI-powered field service knowledge platform for a global digital business and technology transformation company to address knowledge access, service efficiency, and customer satisfaction challenges.
AWSBusiness IntelligenceData Analytics

Enhancing Business Intelligence with AI-Powered Data Integration on AWS

Gazelle AI, a subsidiary of Lightcast, partnered with Matoffo to revolutionize its business intelligence platform through a secure, scalable, cloud-native data infrastructure.
AWS Cloud ArchitectureCI/CD PipelinesEdTech

Disaster Recovery Environment Setup from Scratch

A leading English language assessment platform serving the United States and the United Kingdom partnered with Matoffo to build a comprehensive disaster recovery solution from scratch.
Amazon EKSAWS Cloud ArchitectureHumanitarian Services

AWS Native Kubernetes Solution Implementation

A global humanitarian organization serving 118+ countries partnered with Matoffo to transform their inefficient serverless infrastructure into a scalable, enterprise-grade Kubernetes solution on AWS.

Ready to Unlock
Your Cloud Potential?

Background pattern